Floatz Rating
CCC53/100
Confidence
Indicative
Sponsor
Seagen, a wholly owned subsidiary of Pfizer
Modality
antibody_drug_conjugate
Development Phase
Phase 2
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
38Indicative
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT06003231CT.gov A Study of Disitamab Vedotin in Previously Treated Solid Tumors That Express HER2 | — | Active Not Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
81High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Head And Neck Neoplasm
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Disitamab Vedotin (this asset) | Seagen, a wholly owned subsidiary of Pfizer | P2 | CCC · 53 |
| Fluorouracilum | Rutgers, The State University of New Jersey | P4 | BB |
| Pembrolizumab | Mayo Clinic | P3 | BB |
| Cyclophosphamide | M.D. Anderson Cancer Center | P3 | BB |
| Pralsetinib, Trans- | Hoffmann-La Roche | P3 | B |
| Capecitabine | Rutgers, The State University of New Jersey | P4 | B |
| Cis-Diamminedichloroplatinum Ii | Hoffmann-La Roche | P3 | B |
| 5-fluoro-2-deoxycytidine | National Cancer Institute (NCI) | P2 | B |
| Atezolizumab | University Medical Center Groningen | P2 | B |
+36 more in the Head And Neck Neoplasm cohort
Other indications for Disitamab Vedotin
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Gastroesophageal Junction Adenocarcinoma | — | P2 | BB · 67 |
| HER2 Positive Breast Carcinoma | — | P4 | BB · 64 |
| Colorectal Cancer | — | P4 | B · 61 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Disitamab Vedotin in Head And Neck Neoplasm. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/disitamab-vedotin-head-and-neck-neoplasm
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