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Floatz Rating
B60/100
Confidence
Indicative
v0.2
Sponsor
Merck Sharp & Dohme LLC
Modality
Small molecule
Development Phase
Phase 3
Status
Active
Evidence ledger · v0.2

Clinical Evidence

Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
50Moderate confidence
Detailed axis rationale is planned and will be published soon.
TrialPhaseStatusNPrimary endpointReadout
Study of Pembrolizumab (MK-3475) Versus Chemotherapy in Mismatch Repair Deficient (dMMR) Advanced or Recurrent Endometrial Carcinoma (MK-3475-C93/KEYNOTE-C93/GOG-3064/ENGOT-en15)
Active Not Recruiting
MK-7684A With or Without Other Anticancer Therapies in Participants With Selected Solid Tumors (MK-7684A-005) (KEYVIBE-005)
Completed
Study of Pembrolizumab (MK-3475) in Combination With Adjuvant Chemotherapy With or Without Radiotherapy in Participants With Newly Diagnosed Endometrial Cancer After Surgery With Curative Intent (MK-3475-B21 / KEYNOTE-B21 / ENGOT-en11 / GOG-3053)
Active Not Recruiting

Competitive Position

Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
81High confidence
Detailed axis rationale is planned and will be published soon.

Same indication · Endometrial Cancer

AssetSponsorPhaseRating
Docetaxel (this asset)Merck Sharp & Dohme LLCP3B · 60
Tisotumab VedotinSeagen Inc.P2BBB
LenvatinibMerck Sharp & Dohme LLCP3BB
PembrolizumabEli Lilly and CompanyP3BB
Cis-Diamminedichloroplatinum IiEli Lilly and CompanyP3BB
CarboplatinEli Lilly and CompanyP3BB
AdriamycinYonsei UniversityP3BB
Technetium-99Institut de Cancérologie de LorraineP3BB
Indocyanine GreenInstitut de Cancérologie de LorraineP3BB

+42 more in the Endometrial Cancer cohort

Other indications for Docetaxel

IndicationSponsorPhaseRating
Prostate NeoplasmP4BBB · 73
Pancreatic AdenocarcinomaP2BBB · 72
Cancer Of Unknown Primary SiteP2BBB · 72

Scientific Foundation

Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR

Planned for methodology v0.2.

Development Feasibility

How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR

Planned for methodology v0.2.

Commercial Opportunity

Commercial prize: addressable population, unmet need, and the value case for the indication.
NR

Planned for methodology v0.2.

IP & Exclusivity

Exclusivity position, covering patent protection and freedom-to-operate runway.
NR

Planned for methodology v0.2.

Manufacturing & Supply

Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR

Planned for methodology v0.2.

Related assets

Citation

Floatz Terminal. Docetaxel in Endometrial Cancer. Methodology v0.2.
Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026.
Accessed July 14, 2026.
https://terminal.floatz.ai/assets/docetaxel-endometrial-cancer

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