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Floatz Rating
BB65/100
Confidence
Indicative
v0.2
Sponsor
Merck Sharp & Dohme LLC
Modality
Small molecule
Development Phase
Phase 2
Status
Active
Evidence ledger · v0.2

Clinical Evidence

Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
51High confidence
Detailed axis rationale is planned and will be published soon.
TrialPhaseStatusNPrimary endpointReadout
MK-7684A With or Without Other Anticancer Therapies in Participants With Selected Solid Tumors (MK-7684A-005) (KEYVIBE-005)
Completed
Xenotransplantation of Primary Cancer Samples in Zebrafish Embryos
Unknown
Recombinant EphB4-HSA Fusion Protein With Standard Chemotherapy Regimens in Treating Patients With Advanced or Metastatic Solid Tumors
Active Not Recruiting

Competitive Position

Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
89High confidence
Detailed axis rationale is planned and will be published soon.

Same indication · Gallbladder Cancer

AssetSponsorPhaseRating
Docetaxel (this asset)Merck Sharp & Dohme LLCP2BB · 65
FluorouracilumLisata Therapeutics, Inc.P2BBB
CapecitabineMerck Sharp & Dohme LLCP3BB
OxaliplatinTianjin Medical University Cancer Institute and HospitalP3BB
SevofluraneTokyo Medical and Dental UniversityP4BB
CyclophosphamideMerck Sharp & Dohme LLCP2BB
DesfluraneTokyo Medical and Dental UniversityP4BB
EpirubicinMerck Sharp & Dohme LLCP2BB
CarboplatinMerck Sharp & Dohme LLCP2BB

+42 more in the Gallbladder Cancer cohort

Other indications for Docetaxel

IndicationSponsorPhaseRating
Prostate NeoplasmP4BBB · 73
Pancreatic AdenocarcinomaP2BBB · 72
Cancer Of Unknown Primary SiteP2BBB · 72

Scientific Foundation

Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR

Planned for methodology v0.2.

Development Feasibility

How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR

Planned for methodology v0.2.

Commercial Opportunity

Commercial prize: addressable population, unmet need, and the value case for the indication.
NR

Planned for methodology v0.2.

IP & Exclusivity

Exclusivity position, covering patent protection and freedom-to-operate runway.
NR

Planned for methodology v0.2.

Manufacturing & Supply

Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR

Planned for methodology v0.2.

Related assets

Citation

Floatz Terminal. Docetaxel in Gallbladder Cancer. Methodology v0.2.
Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026.
Accessed July 13, 2026.
https://terminal.floatz.ai/assets/docetaxel-gallbladder-cancer

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