Domvanalimab
Pancreatic Adenosquamous Carcinoma
Explore 12 assets in Pancreatic Adenosquamous Carcinoma →Floatz Rating
CCC48/100
Confidence
Indicative
Sponsor
James Cleary, MD, PhD
Modality
UNKNOWN
Development Phase
Phase 1/2
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
33Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT05419479CT.gov Switch Maintenance in Pancreatic | — | Suspended | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Pancreatic Adenosquamous Carcinoma
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Domvanalimab (this asset) | James Cleary, MD, PhD | P1/2 | CCC · 48 |
| Fluorouracilum | Revolution Medicines, Inc. | P3 | BB |
| Irinotecan | Revolution Medicines, Inc. | P3 | BB |
| Zoldonrasib | Revolution Medicines, Inc. | P3 | B |
| Daraxonrasib | Revolution Medicines, Inc. | P3 | B |
| Cis-Diamminedichloroplatinum Ii | Alliance for Clinical Trials in Oncology | P2/3 | B |
| Minnelide | National Cancer Institute (NCI) | P2 | B |
| Oxaliplatin | Revolution Medicines, Inc. | P3 | B |
| Olaparib | National Cancer Institute (NCI) | P2 | CCC |
+3 more in the Pancreatic Adenosquamous Carcinoma cohort
Other indications for Domvanalimab
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Non-Small Cell Squamous Lung Carcinoma | — | P2 | B · 57 |
| Non-Small Cell Lung Carcinoma | — | P3 | B · 56 |
| Carcinoid Tumor | — | P2 | CCC · 53 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Domvanalimab in Pancreatic Adenosquamous Carcinoma. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/domvanalimab-pancreatic-adenosquamous-carcinoma
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