Floatz Rating
B60/100
Confidence
Indicative
Sponsor
GlaxoSmithKline
Modality
monoclonal_antibody
Development Phase
Phase 3
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
50Indicative
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT06567782CT.gov A Study of Neoadjuvant Dostarlimab Plus Capecitabine Plus Oxaliplatin (CAPEOX) Vs CAPEOX With Previously Untreated T4N0 or Stage III Mismatch Repair Proficient (MMRp)/Microsatellite Stable (MSS) Colon Cancer | — | Recruiting | — | — | — |
NCT05855200CT.gov Study of Perioperative Dostarlimab in Participants With Untreated T4N0 or Stage III dMMR/MSI-H Resectable Colon Cancer | — | Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
81High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Colonic Neoplasm
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Dostarlimab (this asset) | GlaxoSmithKline | P3 | B · 60 |
| Oxaliplatin | First Affiliated Hospital of Guangxi Medical University | P4 | BB |
| Propofol | Hillel Yaffe Medical Center | P4 | BB |
| Ertapenem | University of Ulm | P4 | BB |
| Levofolinic Acid | Asan Medical Center | P2 | BB |
| Sevoflurane | Uppsala University | P4 | BB |
| Capecitabine | First Affiliated Hospital of Guangxi Medical University | P3 | B |
| Tislelizumab | First Affiliated Hospital of Guangxi Medical University | P3 | B |
| Gabapentin | University of Illinois College of Medicine at Peoria | P4 | B |
+38 more in the Colonic Neoplasm cohort
Other indications for Dostarlimab
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Non-Small Cell Lung Carcinoma | — | P3 | BB · 68 |
| Ovarian Carcinoma | — | P3 | BB · 65 |
| Rectal Neoplasm | — | P2 | B · 60 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Dostarlimab in Colonic Neoplasm. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/dostarlimab-colonic-neoplasm
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