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E. Coli Endotoxin

Acute Lymphoblastic Leukemia

Explore 247 assets in Acute Lymphoblastic Leukemia
Floatz Rating
CCC52/100
Confidence
Indicative
v0.2
Sponsor
National Cancer Institute (NCI)
Modality
other_biological
Development Phase
Phase 1/2
Status
Dormant
Evidence ledger · v0.2

Clinical Evidence

Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
37Moderate confidence
Detailed axis rationale is planned and will be published soon.
TrialPhaseStatusNPrimary endpointReadout
Wilm's Tumor 1 Protein Vaccine to Treat Cancers of the Blood
Completed

Competitive Position

Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95Moderate confidence
Detailed axis rationale is planned and will be published soon.

Same indication · Acute Lymphoblastic Leukemia

AssetSponsorPhaseRating
E. Coli Endotoxin (this asset)National Cancer Institute (NCI)P1/2CCC · 52
Gm-CsfXinhua Hospital, Shanghai Jiao Tong University School of MedicineP4BBB
Peripheral Blood Stem Cells, Allogeneic, Cd34 PositiveFred Hutchinson Cancer CenterP2/3BBB
Thioguanine AnhydrousSt. Jude Children's Research HospitalP4BBB
Equine AtgInstituto Nacional de Cancer, BrazilP3BBB
Mercaptopurine AnhydrousDana-Farber Cancer InstituteP4BB
DaunomycinPETHEMA FoundationP4BB
MethotrexatePrincess Maxima Center for Pediatric OncologyP4BB
AsparaginaseCentre Hospitalier Universitaire de NiceP4BB

+42 more in the Acute Lymphoblastic Leukemia cohort

Other indications for E. Coli Endotoxin

IndicationSponsorPhaseRating
FibromyalgiaP2/3B · 60
Myelodysplastic SyndromeP1/2CCC · 52
Chronic Myeloid LeukemiaP1/2CCC · 52

Scientific Foundation

Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR

Planned for methodology v0.2.

Development Feasibility

How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR

Planned for methodology v0.2.

Commercial Opportunity

Commercial prize: addressable population, unmet need, and the value case for the indication.
NR

Planned for methodology v0.2.

IP & Exclusivity

Exclusivity position, covering patent protection and freedom-to-operate runway.
NR

Planned for methodology v0.2.

Manufacturing & Supply

Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR

Planned for methodology v0.2.

Related assets

Citation

Floatz Terminal. E. Coli Endotoxin in Acute Lymphoblastic Leukemia. Methodology v0.2.
Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026.
Accessed July 14, 2026.
https://terminal.floatz.ai/assets/e-coli-endotoxin-acute-lymphoblastic-leukemia

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