Floatz Rating
CC45/100
Confidence
Indicative
Sponsor
Eisai Inc.
Modality
UNKNOWN
Development Phase
Phase 1/2
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
33Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT04008797CT.gov A Study of E7386 in Combination With Other Anticancer Drug(s) in Participants With Solid Tumor | — | Active Not Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
81High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Endometrial Cancer
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| e7386 (this asset) | Eisai Inc. | P1/2 | CC · 45 |
| Tisotumab Vedotin | Seagen Inc. | P2 | BBB |
| Lenvatinib | Merck Sharp & Dohme LLC | P3 | BB |
| Pembrolizumab | Eli Lilly and Company | P3 | BB |
| Cis-Diamminedichloroplatinum Ii | Eli Lilly and Company | P3 | BB |
| Carboplatin | Eli Lilly and Company | P3 | BB |
| Adriamycin | Yonsei University | P3 | BB |
| Technetium-99 | Institut de Cancérologie de Lorraine | P3 | BB |
| Indocyanine Green | Institut de Cancérologie de Lorraine | P3 | BB |
+42 more in the Endometrial Cancer cohort
Other indications for e7386
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Colorectal Neoplasm | — | P1/2 | CCC · 51 |
| Hepatocellular Carcinoma | — | P1/2 | CCC · 48 |
| Liver And Intrahepatic Bile Duct Neoplasm | — | P1/2 | CC · 45 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. e7386 in Endometrial Cancer. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/e7386-endometrial-cancer
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