Floatz Rating
CCC54/100
Confidence
Indicative
Sponsor
Infinity Pharmaceuticals, Inc.
Modality
Small molecule
Development Phase
Phase 2
Status
Dormant
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
42Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT03980041CT.gov Study to Evaluate the Efficacy/Safety of IPI-549 in Combination With Nivolumab in Patients With Advanced Urothelial Carcinoma (MARIO-275) | — | Completed | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
73High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Urinary Bladder Carcinoma
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Eganelisib (this asset) | Infinity Pharmaceuticals, Inc. | P2 | CCC · 54 |
| Cis-Diamminedichloroplatinum Ii | G1 Therapeutics, Inc. | P3 | BBB |
| Trastuzumab | NKGen Biotech, Inc. | P2 | BB |
| Carboplatin | G1 Therapeutics, Inc. | P3 | BB |
| Vinblastine | University of Southern California | P3 | BB |
| Pembrolizumab | Essen Biotech | P3 | BB |
| Cyclophosphamide | Beijing Biotech | P3 | BB |
| Adriamycin | Toray Industries, Inc | P3 | BB |
| Docetaxel | Poniard Pharmaceuticals | P2 | BB |
+42 more in the Urinary Bladder Carcinoma cohort
Other indications for Eganelisib
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Cancer | — | P2 | B · 58 |
| Urothelial Carcinoma | — | P2 | CCC · 54 |
| Renal Cell Carcinoma | — | P2 | CCC · 48 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Eganelisib in Urinary Bladder Carcinoma. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/eganelisib-urinary-bladder-carcinoma
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