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Floatz Rating
BB71/100
Confidence
Indicative
v0.2
Sponsor
Fred Hutchinson Cancer Center
Modality
Small molecule
Development Phase
Phase 2
Status
Dormant
Evidence ledger · v0.2

Clinical Evidence

Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
60High confidence
Detailed axis rationale is planned and will be published soon.
TrialPhaseStatusNPrimary endpointReadout
Genetically Modified Peripheral Blood Stem Cell Transplant in Treating Patients With HIV-Associated Non-Hodgkin or Hodgkin Lymphoma
Withdrawn
Alisertib in Combination With Vorinostat in Treating Patients With Relapsed or Recurrent Hodgkin Lymphoma, B-Cell Non-Hodgkin Lymphoma, or Peripheral T-Cell Lymphoma
Completed
High-Dose Chemotherapy With or Without Total-Body Irradiation Followed by Autologous Stem Cell Transplant in Treating Patients With Hematologic Cancer or Solid Tumors
Completed

Competitive Position

Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
89High confidence
Detailed axis rationale is planned and will be published soon.

Same indication · Intraocular Lymphoma

AssetSponsorPhaseRating
Etoposide (this asset)Fred Hutchinson Cancer CenterP2BB · 71
FludarabineCase Comprehensive Cancer CenterP2BBB
CyclophosphamidePeking Union Medical College HospitalP2BBB
RituximabPeking Union Medical College HospitalP2BBB
DexasonePeking Union Medical College HospitalP2BB
Cyclosporin ANational Cancer Institute (NCI)P2BB
CediranibNational Cancer Institute (NCI)P2BB
BendamustineWake Forest University Health SciencesP2BB
AdriamycinPeking Union Medical College HospitalP2BB

+42 more in the Intraocular Lymphoma cohort

Other indications for Etoposide

IndicationSponsorPhaseRating
Acute Megakaryoblastic LeukemiaP3BBB · 79
Acute Monocytic LeukemiaP3BBB · 79
Acute Myeloblastic Leukemia With MaturationP3BBB · 79

Scientific Foundation

Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR

Planned for methodology v0.2.

Development Feasibility

How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR

Planned for methodology v0.2.

Commercial Opportunity

Commercial prize: addressable population, unmet need, and the value case for the indication.
NR

Planned for methodology v0.2.

IP & Exclusivity

Exclusivity position, covering patent protection and freedom-to-operate runway.
NR

Planned for methodology v0.2.

Manufacturing & Supply

Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR

Planned for methodology v0.2.

Related assets

Citation

Floatz Terminal. Etoposide in Intraocular Lymphoma. Methodology v0.2.
Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026.
Accessed July 13, 2026.
https://terminal.floatz.ai/assets/etoposide-intraocular-lymphoma

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