Floatz Rating
CC43/100
Confidence
Indicative
Sponsor
M.D. Anderson Cancer Center
Modality
Small molecule
Development Phase
Phase 1
Status
Dormant
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
28Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT03420963CT.gov Donor Natural Killer Cells, Cyclophosphamide, and Etoposide in Treating Children and Young Adults With Relapsed or Refractory Solid Tumors | — | Terminated | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Malignant Soft Tissue Neoplasm
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Etoposide (this asset) | M.D. Anderson Cancer Center | P1 | CC · 43 |
| Nivolumab | National Cancer Institute (NCI) | P3 | B |
| Cabozantinib | National Cancer Institute (NCI) | P3 | B |
| Ipilimumab | National Cancer Institute (NCI) | P3 | B |
| Enzalutamide | OHSU Knight Cancer Institute | P2 | B |
| Ptvg-Hp | University of Wisconsin, Madison | P1/2 | CCC |
| Pembrolizumab | University of Wisconsin, Madison | P1/2 | CCC |
| Cord Blood-Derived Expanded Allogeneic Natural Killer Cells | M.D. Anderson Cancer Center | P1 | CC |
| Cyclophosphamide | M.D. Anderson Cancer Center | P1 | CC |
Other indications for Etoposide
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Acute Megakaryoblastic Leukemia | — | P3 | BBB · 79 |
| Acute Monocytic Leukemia | — | P3 | BBB · 79 |
| Acute Myeloblastic Leukemia With Maturation | — | P3 | BBB · 79 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Etoposide in Malignant Soft Tissue Neoplasm. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/etoposide-malignant-soft-tissue-neoplasm
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