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Floatz Rating
B60/100
Confidence
Indicative
v0.2
Sponsor
Novartis Pharmaceuticals
Modality
Small molecule
Development Phase
Phase 2
Status
Dormant
Evidence ledger · v0.2

Clinical Evidence

Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
45High confidence
Detailed axis rationale is planned and will be published soon.
TrialPhaseStatusNPrimary endpointReadout
Study of Safety and Efficacy of Alpelisib With Everolimus or Alpelisib With Everolimus and Exemestane in Advanced Breast Cancer Patients, Renal Cell Cancer and Pancreatic Tumors
Completed
Treatment of Refractory Metastatic Renal Cell Carcinoma With Bevacizumab and RAD001 (Everolimus)
Terminated

Competitive Position

Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
89High confidence
Detailed axis rationale is planned and will be published soon.

Same indication · Kidney Neoplasm

AssetSponsorPhaseRating
Everolimus (this asset)Novartis PharmaceuticalsP2B · 60
AxitinibPfizerP3BB
IpilimumabPfizerP4BB
NivolumabBristol-Myers SquibbP4BB
AdriamycinMerck Sharp & Dohme LLCP2BB
SorafenibPfizerP3B
TemsirolimusPfizerP3B
Alpha-InterferonPfizerP3B
VolitinibAstraZenecaP3B

+41 more in the Kidney Neoplasm cohort

Other indications for Everolimus

IndicationSponsorPhaseRating
Tuberous SclerosisP3BBB · 76
Hormone Receptor-Positive Breast CancerP4BBB · 75
Hodgkins LymphomaP2BBB · 74

Scientific Foundation

Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR

Planned for methodology v0.2.

Development Feasibility

How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR

Planned for methodology v0.2.

Commercial Opportunity

Commercial prize: addressable population, unmet need, and the value case for the indication.
NR

Planned for methodology v0.2.

IP & Exclusivity

Exclusivity position, covering patent protection and freedom-to-operate runway.
NR

Planned for methodology v0.2.

Manufacturing & Supply

Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR

Planned for methodology v0.2.

Related assets

Citation

Floatz Terminal. Everolimus in Kidney Neoplasm. Methodology v0.2.
Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026.
Accessed July 14, 2026.
https://terminal.floatz.ai/assets/everolimus-kidney-neoplasm

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