Floatz Rating
B63/100
Confidence
Indicative
Sponsor
Alliance for Clinical Trials in Oncology
Modality
Small molecule
Development Phase
Phase 3
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
50Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT06075953CT.gov DCIS: RECAST Trial Ductal Carcinoma In Situ: Re-Evaluating Conditions for Active Surveillance Suitability as Treatment | — | Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
89High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Ductal Breast Carcinoma In Situ
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Exemestane (this asset) | Alliance for Clinical Trials in Oncology | P3 | B · 63 |
| Ropivacaine | Zealand University Hospital | P4 | BB |
| Sufentanyl | Zealand University Hospital | P4 | BB |
| Letrozole | Alliance for Clinical Trials in Oncology | P3 | BB |
| (Z)-Endoxifen | Robert Bosch Gesellschaft für Medizinische Forschung mbH (RBMF) | P2 | BB |
| Metformin | M.D. Anderson Cancer Center | P3 | BB |
| Anastrozole | Alliance for Clinical Trials in Oncology | P3 | BB |
| Oxybutynin | Academic and Community Cancer Research United | P3 | BB |
| Tamoxifen | National Cancer Institute (NCI) | P3 | BB |
+42 more in the Ductal Breast Carcinoma In Situ cohort
Other indications for Exemestane
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Estrogen-Receptor Positive Breast Cancer | — | P4 | BBB · 75 |
| Hormone Receptor-Positive Breast Cancer | — | P4 | BBB · 75 |
| Her2-Receptor Negative Breast Cancer | — | P4 | BBB · 73 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Exemestane in Ductal Breast Carcinoma In Situ. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/exemestane-ductal-breast-carcinoma-in-situ
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