Floatz Rating
BB68/100
Confidence
Indicative
Sponsor
paresh Dandona
Modality
Small molecule
Development Phase
Phase 4 / Approved
Status
Dormant
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
54High confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT04638400CT.gov Anti-inflammatory Effects of Simvastatin | — | Terminated | — | — | — |
NCT00079638CT.gov Comparative Efficacy Evaluation of Lipids When Treated With Niaspan & Statin or Other Lipid-Modifying Therapies-COMPELL | — | Completed | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
89High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Atherosclerosis
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Ezetimibe (this asset) | paresh Dandona | Approved | BB · 68 |
| Aspirin | Rajaie Cardiovascular Medical and Research Center | P4 | BBB |
| Simvastatin | Northern California Institute of Research and Education | P4 | BBB |
| Atorvastatin | Erasmus Medical Center | P4 | BB |
| Clopidogrel | Ewha Womans University Seoul Hospital | P4 | BB |
| Cilostazol | Asan Medical Center | P4 | BB |
| Rosuvastatin | Emory University | P4 | BB |
| Testosterone Undecylate | Brigham and Women's Hospital | P4 | BB |
| Alteplase | Alexandria University | P4 | BB |
+37 more in the Atherosclerosis cohort
Other indications for Ezetimibe
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Coronary Artery Disorder | — | P4 | BBB · 76 |
| Inherited Lipid Metabolism Disorder | — | P4 | BBB · 75 |
| Hyperlipidemia | — | P4 | BBB · 74 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Ezetimibe in Atherosclerosis. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/ezetimibe-atherosclerosis
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