Ezetimibe
Atherosclerotic Cardiovascular Disease
Explore 16 assets in Atherosclerotic Cardiovascular Disease →Floatz Rating
D30/100
Confidence
Indicative
Sponsor
Novartis Pharmaceuticals
Modality
Small molecule
Development Phase
N/A
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
15Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT05974345CT.gov In Silico Study Assessing the Impact of Inclisiran on Major Adverse Cardiovascular Events in Patients With Established Cardiovascular Disease | — | Completed | — | — | — |
NCT05705804CT.gov Effects of Pitavastatin or Combination of Pitavastatin and Ezetimibe on Glucose Metabolism Compared to AtoRvastatin in atheroscLerotic Cardiovascular Disease Patients With Metabolic Syndrome: The EZ-PEARL Randomized Trial | — | Unknown | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
89High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Atherosclerotic Cardiovascular Disease
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Ezetimibe (this asset) | Novartis Pharmaceuticals | N/A | D · 30 |
| Eicosapentaenoic Acid Ethyl Ester | Kobe University | P4 | BB |
| Umbellatine | China National Center for Cardiovascular Diseases | P4 | BB |
| Orforglipron | Eli Lilly and Company | P3 | B |
| Retatrutide | Eli Lilly and Company | P3 | B |
| Inclisiran | Novartis Pharmaceuticals | P3 | B |
| Tirzepatide | Brigham and Women's Hospital | P4 | B |
| Maridebart Cafraglutide | Amgen | P3 | B |
| [18F]AlF-OC | Universitaire Ziekenhuizen KU Leuven | P2 | CCC |
+8 more in the Atherosclerotic Cardiovascular Disease cohort
Other indications for Ezetimibe
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Coronary Artery Disorder | — | P4 | BBB · 76 |
| Inherited Lipid Metabolism Disorder | — | P4 | BBB · 75 |
| Hyperlipidemia | — | P4 | BBB · 74 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Ezetimibe in Atherosclerotic Cardiovascular Disease. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/ezetimibe-atherosclerotic-cardiovascular-disease
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