Fludeoxyglucose
Astrocytoma, IDH-Mutant, Grade 4
Explore 12 assets in Astrocytoma, IDH-Mutant, Grade 4 →Floatz Rating
CC43/100
Confidence
Indicative
Sponsor
City of Hope Medical Center
Modality
Small molecule
Development Phase
Phase 1
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
28Indicative
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT06815029CT.gov Intracranial Genetically Modified Immune Cells (TGFβR2KO/IL13Rα2 CAR T-Cells) for the Treatment of Recurrent or Progressive Glioblastoma or Grade 3 or 4 IDH-Mutant Astrocytoma | — | Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
89High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Astrocytoma, IDH-Mutant, Grade 4
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Fludeoxyglucose (this asset) | City of Hope Medical Center | P1 | CC · 43 |
| Nivolumab | Andrew P. Groves | P2 | B |
| Safusidenib | Nuvation Bio Inc. | P3 | B |
| gi-102 | Mayo Clinic | P2 | CCC |
| Ipilimumab | National Cancer Institute (NCI) | P2 | CCC |
| Pembrolizumab | Mayo Clinic | P2 | CCC |
| Ribociclib | St. Jude Children's Research Hospital | P1 | CC |
| Nivestim | St. Jude Children's Research Hospital | P1 | CC |
| Trametinib | St. Jude Children's Research Hospital | P1 | CC |
+7 more in the Astrocytoma, IDH-Mutant, Grade 4 cohort
Other indications for Fludeoxyglucose
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Non-Small Cell Lung Carcinoma | — | P3 | BB · 69 |
| Prostate Carcinoma | — | P2/3 | BB · 69 |
| Breast Carcinoma | — | P2 | BB · 68 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Fludeoxyglucose in Astrocytoma, IDH-Mutant, Grade 4. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/fludeoxyglucose-astrocytoma-idh-mutant-grade-4
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