Floatz Rating
B62/100
Confidence
Indicative
Sponsor
Beijing Tiantan Hospital
Modality
Small molecule
Development Phase
Phase 4 / Approved
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
60High confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT05169021CT.gov Folic Acid and Intensive Antihypertensive Therapy for Hypertension With CSVD | — | Not Yet Recruiting | — | — | — |
NCT00106886CT.gov HOPE-2 Study (Heart Outcomes Prevention Evaluation-2 Study) | — | Unknown | — | — | — |
NCT00354081CT.gov WENBIT - Western Norway B Vitamin Intervention Trial | — | Completed | — | — | — |
NCT00097669CT.gov VITATOPS: A Study of VITAmins TO Prevent Stroke | — | Completed | — | — | — |
NCT00004734CT.gov Vitamin Therapy for Prevention of Stroke | — | Completed | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
65High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Stroke Disorder
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Folic Acid (this asset) | Beijing Tiantan Hospital | Approved | B · 62 |
| Aggrenox | Boehringer Ingelheim | P4 | BBB |
| Incobotulinumtoxina | Parc de Salut Mar | P4 | BBB |
| Atenolol | Northern California Institute of Research and Education | P4 | BBB |
| Tenecteplase | Assistance Publique - Hôpitaux de Paris | P4 | BBB |
| Dextromethorphan | University of Florida | P4 | BBB |
| Rivaroxaban | China National Center for Cardiovascular Diseases | P4 | BBB |
| Nerinetide | NoNO Inc. | P3 | BBB |
| Aspirin | China National Center for Cardiovascular Diseases | P4 | BB |
+42 more in the Stroke Disorder cohort
Other indications for Folic Acid
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Hyperhomocysteinemia | — | P4 | BBB · 76 |
| Myocardial Infarction | — | P4 | BBB · 72 |
| Polycystic Ovary Syndrome | — | P4 | BB · 70 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Folic Acid in Stroke Disorder. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/folic-acid-stroke-disorder
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