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Floatz Rating
C37/100
Confidence
Indicative
v0.2
Sponsor
M.D. Anderson Cancer Center
Modality
Small molecule
Development Phase
Phase 1
Status
Active
Evidence ledger · v0.2

Clinical Evidence

Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
28Indicative
Detailed axis rationale is planned and will be published soon.
TrialPhaseStatusNPrimary endpointReadout
Phase I, Open-Label, Study of Tumor Infiltrating Lymphocytes Engineered With Membrane Bound IL15 Plus Acetazolamide in Adult Patients With Metastatic Melanoma
Active Not Recruiting

Competitive Position

Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
65High confidence
Detailed axis rationale is planned and will be published soon.

Same indication · Melanoma

AssetSponsorPhaseRating
Furosemide (this asset)M.D. Anderson Cancer CenterP1C · 37
Gm-CsfUltimovacs ASAP4BBB
CyclophosphamidePrimmune Therapeutics, Inc.P4BB
IpilimumabM.D. Anderson Cancer CenterP4BB
DacarbazineSuzhou BlueHorse Therapeutics Co., Ltd.P3BB
SargramostimMayo ClinicP3BB
PembrolizumabBiocon Biologics UK PLCP4BB
CediranibM.D. Anderson Cancer CenterP3BB
NivolumabBristol-Myers SquibbP4BB

+42 more in the Melanoma cohort

Other indications for Furosemide

IndicationSponsorPhaseRating
Cirrhosis Of LiverP4BB · 67
PreeclampsiaP4B · 61
Acute Myeloid LeukemiaP2B · 59

Scientific Foundation

Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR

Planned for methodology v0.2.

Development Feasibility

How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR

Planned for methodology v0.2.

Commercial Opportunity

Commercial prize: addressable population, unmet need, and the value case for the indication.
NR

Planned for methodology v0.2.

IP & Exclusivity

Exclusivity position, covering patent protection and freedom-to-operate runway.
NR

Planned for methodology v0.2.

Manufacturing & Supply

Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR

Planned for methodology v0.2.

Related assets

Citation

Floatz Terminal. Furosemide in Melanoma. Methodology v0.2.
Rated under v0.2 effective July 8, 2026. Last refreshed July 14, 2026.
Accessed July 14, 2026.
https://terminal.floatz.ai/assets/furosemide-melanoma

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