Gemcabene
Familial Partial Lipodystrophy
Floatz Rating
CCC52/100
Confidence
Indicative
Sponsor
Elif Oral
Modality
UNKNOWN
Development Phase
Phase 1/2
Status
Dormant
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
37Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT03508687CT.gov Study of Gemcabene in Adults With FPLD | — | Completed | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95Indicative
Detailed axis rationale is planned and will be published soon.
Same indication · Familial Partial Lipodystrophy
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Gemcabene (this asset) | Elif Oral | P1/2 | CCC · 52 |
| R-Methuleptin | University of Michigan | P2 | B |
| Vupanorsen | Akcea Therapeutics | P2 | B |
Other indications for Gemcabene
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Hypertriglyceridemia | — | P1/2 | CCC · 52 |
| Metabolic Dysfunction-Associated Steatotic Liver Disease | — | P2 | CCC · 51 |
| Metabolic Dysfunction-Associated Steatohepatitis | — | P1/2 | CCC · 50 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Gemcabene in Familial Partial Lipodystrophy. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/gemcabene-familial-partial-lipodystrophy
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