Gnrh
Hyperprolactinemia
Floatz Rating
CC47/100
Confidence
Indicative
Sponsor
Massachusetts General Hospital
Modality
protein_peptide
Development Phase
Phase 1
Status
Dormant
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
32Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT00914823CT.gov Kisspeptin Administration in the Adult | — | Completed | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Hyperprolactinemia
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Gnrh (this asset) | Massachusetts General Hospital | P1 | CC · 47 |
| Risperidone | Si Tianmei | P4 | BB |
| Paliperidone | Si Tianmei | P4 | BB |
| Bromocriptin | University Hospital, Bonn | P3 | B |
| Bushen Culuan Decoction | Xiyuan Hospital of China Academy of Chinese Medical Sciences | P2 | CCC |
| Kisspeptin 112-121 | Massachusetts General Hospital | P1 | CC |
| Metformin | Taipei Medical University Hospital | N/A | D |
Other indications for Gnrh
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Prostate Disorder | — | P2 | B · 57 |
| Down Syndrome | — | P2/3 | B · 57 |
| Cognitive Disorder | — | P2/3 | B · 57 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Gnrh in Hyperprolactinemia. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/gnrh-hyperprolactinemia
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