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Granisetron

Mast Cell Leukemia

Explore 10 assets in Mast Cell Leukemia
Floatz Rating
B57/100
Confidence
Indicative
v0.2
Sponsor
Stanford University
Modality
Small molecule
Development Phase
Phase 2
Status
Dormant
Evidence ledger · v0.2

Clinical Evidence

Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
42Moderate confidence
Detailed axis rationale is planned and will be published soon.
TrialPhaseStatusNPrimary endpointReadout
Phase 2 Trial of Prophylactic Rituximab Therapy for Prevention of CGVHD
Completed

Competitive Position

Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.

Same indication · Mast Cell Leukemia

AssetSponsorPhaseRating
Granisetron (this asset)Stanford UniversityP2B · 57
Cyclosporin AStanford UniversityP2BB
FludarabineFred Hutchinson Cancer CenterP2BB
AvapritinibBlueprint Medicines CorporationP2BB
AlemtuzumabFred Hutchinson Cancer CenterP2B
NivestimStanford UniversityP2B
Brentuximab VedotinJason Robert GotlibP2B
RituximabStanford UniversityP2B
DeferasiroxWake Forest University Health SciencesP2B

+16 more in the Mast Cell Leukemia cohort

Other indications for Granisetron

IndicationSponsorPhaseRating
Cancer Of Unknown Primary SiteP3BB · 71
Myofascial Pain SyndromeP4BB · 69
Temporomandibular Joint DisorderP4BB · 69

Scientific Foundation

Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR

Planned for methodology v0.2.

Development Feasibility

How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR

Planned for methodology v0.2.

Commercial Opportunity

Commercial prize: addressable population, unmet need, and the value case for the indication.
NR

Planned for methodology v0.2.

IP & Exclusivity

Exclusivity position, covering patent protection and freedom-to-operate runway.
NR

Planned for methodology v0.2.

Manufacturing & Supply

Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR

Planned for methodology v0.2.

Related assets

Citation

Floatz Terminal. Granisetron in Mast Cell Leukemia. Methodology v0.2.
Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026.
Accessed July 14, 2026.
https://terminal.floatz.ai/assets/granisetron-mast-cell-leukemia

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