Floatz Rating
CCC53/100
Confidence
Indicative
Sponsor
Memorial Sloan Kettering Cancer Center
Modality
Cell therapy
Development Phase
Phase 2
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
38Indicative
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT04644016CT.gov Cord Blood Transplant in Children and Young Adults With Blood Cancers and Non-malignant Disorders | — | Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Bone Marrow Failure Syndrome
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Hpc, Cord Blood (this asset) | Memorial Sloan Kettering Cancer Center | P2 | CCC · 53 |
| Fludarabine | Fred Hutchinson Cancer Center | P2/3 | BBB |
| Cyclophosphamide | Memorial Sloan Kettering Cancer Center | P2/3 | BBB |
| Thiotepa | Fred Hutchinson Cancer Center | P2 | BB |
| Busulfanum | Memorial Sloan Kettering Cancer Center | P2/3 | BB |
| Alemtuzumab | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | P2/3 | BB |
| Melphalan | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | P2 | B |
| Treosulfan | Fred Hutchinson Cancer Center | P2 | B |
| Horse Anti-Thymocyte Globulin | New York Medical College | P2/3 | B |
+22 more in the Bone Marrow Failure Syndrome cohort
Other indications for Hpc, Cord Blood
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Acute Lymphoblastic Leukemia | — | P2 | B · 60 |
| Myelodysplastic Syndrome | — | P2 | CCC · 55 |
| Non-Hodgkin Lymphoma | — | P2 | CCC · 55 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Hpc, Cord Blood in Bone Marrow Failure Syndrome. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/hpc-cord-blood-bone-marrow-failure-syndrome
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