Seprehvir
Malignant Peripheral Nerve Sheath Tumor
Explore 15 assets in Malignant Peripheral Nerve Sheath Tumor →Floatz Rating
CC47/100
Confidence
Indicative
Sponsor
Timothy Cripe
Modality
other_biological
Development Phase
Phase 1
Status
Dormant
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
32Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT00931931CT.gov HSV1716 in Patients With Non-Central Nervous System (Non-CNS) Solid Tumors | — | Completed | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Malignant Peripheral Nerve Sheath Tumor
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Seprehvir (this asset) | Timothy Cripe | P1 | CC · 47 |
| Cyclophosphamide | St. Jude Children's Research Hospital | P2 | B |
| Fludarabine | St. Jude Children's Research Hospital | P2 | B |
| Pembrolizumab | Seattle Children's Hospital | P1/2 | CCC |
| Nivolumab | National Cancer Institute (NCI) | P2 | CCC |
| Thiotepa | M.D. Anderson Cancer Center | P2 | CCC |
| Selinexor | Memorial Sloan Kettering Cancer Center | P2 | CCC |
| Telaglenastat | National Cancer Institute (NCI) | P2 | CCC |
| Etoposide | M.D. Anderson Cancer Center | P2 | CCC |
+13 more in the Malignant Peripheral Nerve Sheath Tumor cohort
Other indications for Seprehvir
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Neoplasm | — | P1 | CC · 47 |
| Clivus Chordoma | — | P1 | CC · 47 |
| Wilms Tumor | — | P1 | CC · 46 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Seprehvir in Malignant Peripheral Nerve Sheath Tumor. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/hsv-1716-malignant-peripheral-nerve-sheath-tumor
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