Floatz Rating
CCC53/100
Confidence
Indicative
Sponsor
University of Texas Southwestern Medical Center
Modality
Small molecule
Development Phase
Phase 1
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
39Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT02051335CT.gov Roflumilast and Donepezil to Reverse Scopolamine Induced Cognitive Deficits in Healthy Adults | — | Completed | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Amnestic Disorder
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Hyoscine (this asset) | University of Texas Southwestern Medical Center | P1 | CCC · 53 |
| Madopar | Peking University Third Hospital | P4 | BB |
| Celecoxib | University of California, Los Angeles | P3 | B |
| Atomoxetine | Icahn School of Medicine at Mount Sinai | P2 | B |
| Ladostigil Hemitartrate | Avraham Pharmaceuticals Ltd | P2 | B |
| Metformin | University of Pennsylvania | P2 | B |
| Cot | Evon Medics LLC | P2 | CCC |
| Cort108297 | Johns Hopkins University | P2 | CCC |
| Prilocaine | University of Dublin, Trinity College | P1/2 | CCC |
+5 more in the Amnestic Disorder cohort
Other indications for Hyoscine
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Morbid Obesity | — | P4 | B · 62 |
| Major Depressive Disorder | — | P4 | B · 61 |
| Depressive Disorder | — | P4 | B · 60 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Hyoscine in Amnestic Disorder. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/hyoscine-amnestic-disorder
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