Floatz Rating
B60/100
Confidence
Indicative
Sponsor
Academic and Community Cancer Research United
Modality
Small molecule
Development Phase
Phase 2
Status
Dormant
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
45High confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT04665115CT.gov Ibrutinib for the Treatment of Patients With B-Cell Malignancies Who Are Infected With Coronavirus Disease 2019 (COVID-19) | — | Withdrawn | — | — | — |
NCT04439006CT.gov Ibrutinib for the Treatment of COVID-19 in Patients Requiring Hospitalization | — | Completed | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · COVID-19
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Ibrutinib (this asset) | Academic and Community Cancer Research United | P2 | B · 60 |
| Recombinant Adenovirus Type 5 Carrying The Gene For Severe Acute Respiratory Syndrome Coronavirus 2 (Sars-Cov-2) Spike Glycoprotein (Cansino Biologics) | Seventh Medical Center of PLA General Hospital | P3 | BBB |
| Serostim | ClinAmygate | P4 | BB |
| cc-220 | Nguyen Thi Trieu, MD | P4 | BB |
| Tocilizumab | National Cancer Institute (NCI) | P3 | BB |
| Oxygen | Jay C. Buckey Jr. | P4 | BB |
| Sotrovimab | Fred Hutchinson Cancer Center | P2/3 | B |
| Niclosamide | Cambridge University Hospitals NHS Foundation Trust | P2/3 | B |
| Gam-Covid-Vac | Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation | P3 | B |
+42 more in the COVID-19 cohort
Other indications for Ibrutinib
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Lymphoid Leukemia | — | P4 | BBB · 72 |
| Waldenstrom Macroglobulinemia | — | P4 | BB · 70 |
| B-Cell Chronic Lymphocytic Leukemia | — | P4 | BB · 70 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
- Recombinant Adenovirus Type 5 Carrying The Gene For Severe Acute Respiratory Syndrome Coronavirus 2 (Sars-Cov-2) Spike Glycoprotein (Cansino Biologics)Seventh Medical Center of PLA General HospitalBBB
- SerostimClinAmygateBB
- cc-220Nguyen Thi Trieu, MDBB
- TocilizumabNational Cancer Institute (NCI)BB
- OxygenJay C. Buckey Jr.BB
Citation
Floatz Terminal. Ibrutinib in COVID-19. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/ibrutinib-covid-19
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