Floatz Rating
BB65/100
Confidence
Indicative
Sponsor
St Joseph University, Beirut, Lebanon
Modality
Small molecule
Development Phase
Phase 4 / Approved
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
50Indicative
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT03060434CT.gov Pentoxifylline and Lumbar Radiculopathy | — | Active Not Recruiting | — | — | — |
NCT02777320CT.gov Comparison of Intravenous Ibuprofen and Paracetamol in Patients With Sciatica Presented to the Emergency Department | — | Unknown | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Sciatica
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Ibuprofen (this asset) | St Joseph University, Beirut, Lebanon | Approved | BB · 65 |
| Dexasone | University of Miami | P4 | BBB |
| Lidocaine | C.L.A.Vleggeert-Lankamp | P4 | BBB |
| Nepenthe | Akdeniz University | P4 | BB |
| Naproxen | Ostfold Hospital Trust | P4 | BB |
| Prednisone | Kaiser Permanente | P3 | BB |
| (Rs)-Ketoprofen | University Hospital, Grenoble | P4 | BB |
| Pentoxifylline | St Joseph University, Beirut, Lebanon | P4 | BB |
| Kenacort | University of Miami | P4 | BB |
+36 more in the Sciatica cohort
Other indications for Ibuprofen
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Chronic Pain Syndrome | — | P4 | BBB · 72 |
| Migraine Disorder | — | P4 | BBB · 72 |
| Relapsing-Remitting Multiple Sclerosis | — | P4 | BB · 68 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Ibuprofen in Sciatica. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/ibuprofen-sciatica
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