Icaspase9-Transduced T Cells
Epstein-Barr Virus Infection
Explore 11 assets in Epstein-Barr Virus Infection →Floatz Rating
CC43/100
Confidence
Indicative
Sponsor
Baylor College of Medicine
Modality
Cell therapy
Development Phase
Phase 1
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
28Indicative
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT01494103CT.gov Administration of Donor T Cells With the Caspase-9 Suicide Gene | — | Active Not Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Epstein-Barr Virus Infection
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Icaspase9-Transduced T Cells (this asset) | Baylor College of Medicine | P1 | CC · 43 |
| Rituximab | Jennifer Amengual | P2 | BB |
| L-Dep | Beijing Friendship Hospital | P3 | B |
| Bortezomib | Massachusetts General Hospital | P2 | B |
| Baltaleucel-T | Cell Medica Ltd | P2 | CCC |
| Nivolumab | National Cancer Institute (NCI) | P2 | CCC |
| Tucidinostat | Huiqiang Huang | P2 | CCC |
| Tabelecleucel | Pierre Fabre Medicament | P2 | CCC |
| Epstein-Barr Virus Specific T-Lymphocytes | Jessie L. Alexander | P1/2 | CCC |
+8 more in the Epstein-Barr Virus Infection cohort
Other indications for Icaspase9-Transduced T Cells
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Hereditary Hemophagocytic Lymphohistiocytosis | — | P1 | CC · 43 |
| X-Linked Lymphoproliferative Syndrome | — | P1 | CC · 43 |
| Chronic Myeloid Leukemia | — | P1 | CC · 41 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Icaspase9-Transduced T Cells in Epstein-Barr Virus Infection. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/icaspase9-transduced-t-cells-epstein-barr-virus-infection
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