Immunoglobulin G1 [351-Alanine,386-Alanine,387-Alanine] Anti-(Human Epidermal Growth Factor Receptor Her2) (Human-Mus Musculus Monoclonal Imm2902 ?1-Chain), Disulfide With 1-125-Signal Regulatory Protein ? [80-Alanine] (Human Isoform 4 Variant) Fusion Protein With Peptide Linker ((Ggggs)3) Fusion Protein With Human-Mus Musculus Monoclonal Imm2902 ?-Chain, Dimer
Gastric Cancer
Explore 281 assets in Gastric Cancer →Floatz Rating
CC43/100
Confidence
Indicative
Sponsor
ImmuneOnco Biopharmaceuticals (Shanghai) Inc.
Modality
monoclonal_antibody
Development Phase
Phase 1
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
28Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT05076591CT.gov IMM2902, a HER2/SIRPα Bispecific MAb-Trap Antibody-receptor Fusion Protein, in Patients with HER2-expressing Advanced Solid Tumors | — | Suspended | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
89High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Gastric Cancer
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Immunoglobulin G1 [351-Alanine,386-Alanine,387-Alanine] Anti-(Human Epidermal Growth Factor Receptor Her2) (Human-Mus Musculus Monoclonal Imm2902 ?1-Chain), Disulfide With 1-125-Signal Regulatory Protein ? [80-Alanine] (Human Isoform 4 Variant) Fusion Protein With Peptide Linker ((Ggggs)3) Fusion Protein With Human-Mus Musculus Monoclonal Imm2902 ?-Chain, Dimer (this asset) | ImmuneOnco Biopharmaceuticals (Shanghai) Inc. | P1 | CC · 43 |
| Rivoceranib | Jiangsu Hansoh Pharmaceutical Co., Ltd. | P4 | BBB |
| Fluorouracilum | I-Mab Biopharma US Limited | P4 | BB |
| Oxaliplatin | Qilu Pharmaceutical Co., Ltd. | P3 | BB |
| Pembrolizumab | Eikon Therapeutics | P3 | BB |
| Irinotecan | Shenzhen Xinhe Biomedical | P4 | BB |
| Capecitabine | I-Mab Biopharma US Limited | P3 | BB |
| Docetaxel | Jiangsu Hansoh Pharmaceutical Co., Ltd. | P3 | BB |
| Cis-Diamminedichloroplatinum Ii | Qilu Pharmaceutical Co., Ltd. | P3 | BB |
+42 more in the Gastric Cancer cohort
Other indications for Immunoglobulin G1 [351-Alanine,386-Alanine,387-Alanine] Anti-(Human Epidermal Growth Factor Receptor Her2) (Human-Mus Musculus Monoclonal Imm2902 ?1-Chain), Disulfide With 1-125-Signal Regulatory Protein ? [80-Alanine] (Human Isoform 4 Variant) Fusion Protein With Peptide Linker ((Ggggs)3) Fusion Protein With Human-Mus Musculus Monoclonal Imm2902 ?-Chain, Dimer
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Cholangiocarcinoma | — | P1/2 | CCC · 48 |
| Gastric Carcinoma | — | P1/2 | CC · 47 |
| Cancer | — | P1/2 | CC · 45 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Immunoglobulin G1 [351-Alanine,386-Alanine,387-Alanine] Anti-(Human Epidermal Growth Factor Receptor Her2) (Human-Mus Musculus Monoclonal Imm2902 ?1-Chain), Disulfide With 1-125-Signal Regulatory Protein ? [80-Alanine] (Human Isoform 4 Variant) Fusion Protein With Peptide Linker ((Ggggs)3) Fusion Protein With Human-Mus Musculus Monoclonal Imm2902 ?-Chain, Dimer in Gastric Cancer. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/immunoglobulin-g1-351-alanine386-alanine387-alanine-anti-human-epidermal-growth-factor-receptor-her2-human-mus-musculus-monoclonal-imm2902-1-chain-disulfide-with-1-125-signal-regulatory-protein-80-alanine-human-isoform-4-variant-fusion-protein-with-peptide-linker-ggggs3-fusion-protein-with-human-mus-musculus-monoclonal-imm2902-chain-dimer-gastric-cancer
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