Immunoglobulin G4 [221-Proline], Anti-(Human Programmed Cell Death Protein 1) (Human Monoclonal Sg001 ?4-Chain), Disulfide With Human Monoclonal Sg001 ?-Chain, Dimer
Peripheral T-Cell Lymphoma, Not Otherwise Specified
Explore 128 assets in Peripheral T-Cell Lymphoma, Not Otherwise Specified →Floatz Rating
CCC48/100
Confidence
Indicative
Sponsor
Sun Yat-Sen University Cancer Center
Modality
monoclonal_antibody
Development Phase
Phase 1/2
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
33Indicative
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT07288814CT.gov Mitoxantrone Hydrochloride Liposome and Enlonstobart Combination Treatment in Patients With Relapsed or Refractory Peripheral T Cell Lymphoma (PTCL) | — | Not Yet Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Peripheral T-Cell Lymphoma, Not Otherwise Specified
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Immunoglobulin G4 [221-Proline], Anti-(Human Programmed Cell Death Protein 1) (Human Monoclonal Sg001 ?4-Chain), Disulfide With Human Monoclonal Sg001 ?-Chain, Dimer (this asset) | Sun Yat-Sen University Cancer Center | P1/2 | CCC · 48 |
| Pralatrexate | Peking University People's Hospital | P4 | BBB |
| Adriamycin | BeBetter Med Inc | P4 | BBB |
| Prednisone | Tarapeutics Science Inc. | P4 | BBB |
| Cyclophosphamide | Tarapeutics Science Inc. | P4 | BBB |
| (+)-Vincristine | BeBetter Med Inc | P4 | BBB |
| Romidepsin | University of Virginia | P3 | BBB |
| Rivoceranib | Ruijin Hospital | P4 | BBB |
| Tucidinostat | Ruijin Hospital | P4 | BB |
+42 more in the Peripheral T-Cell Lymphoma, Not Otherwise Specified cohort
Other indications for Immunoglobulin G4 [221-Proline], Anti-(Human Programmed Cell Death Protein 1) (Human Monoclonal Sg001 ?4-Chain), Disulfide With Human Monoclonal Sg001 ?-Chain, Dimer
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Colorectal Cancer | — | P2/3 | CCC · 55 |
| Non-Small Cell Lung Carcinoma | — | P3 | CCC · 54 |
| Hepatocellular Carcinoma | — | P1/2 | CC · 45 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Immunoglobulin G4 [221-Proline], Anti-(Human Programmed Cell Death Protein 1) (Human Monoclonal Sg001 ?4-Chain), Disulfide With Human Monoclonal Sg001 ?-Chain, Dimer in Peripheral T-Cell Lymphoma, Not Otherwise Specified. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/immunoglobulin-g4-221-proline-anti-human-programmed-cell-death-protein-1-human-monoclonal-sg001-4-chain-disulfide-with-human-monoclonal-sg001-chain-dimer-peripheral-t-cell-lymphoma-not-otherwise-specified
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