Floatz Rating
CCC53/100
Confidence
Indicative
Sponsor
City of Hope Medical Center
Modality
Small molecule
Development Phase
Phase 2
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
38High confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT06672224CT.gov Indocyanine Green Fluoroscopy and SPY Angiography for the Assessment of Lymphatic Structure in Breast Cancer Patients at Risk for Breast Cancer-Related Lymphedema | — | Withdrawn | — | — | — |
NCT05094102CT.gov Intraoperative Evaluation of Axillary Lymphatics | — | Completed | — | — | — |
NCT03572998CT.gov Lymphatic Function in Patients Who Have Undergone Breast Cancer Treatment | — | Unknown | — | — | — |
NCT01276054CT.gov Sentinel and/or Axillary Lymph Node Biopsy With or Without Axillary Reverse Mapping in Reducing Incidence and Severity of Arm Lymphedema in Stage 0-2 Patients. | — | Terminated | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
89High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Lymphedema
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Indocyanine Green (this asset) | City of Hope Medical Center | P2 | CCC · 53 |
| Pycnogenol | National Center for Complementary and Integrative Health (NCCIH) | P2 | B |
| Tacrolimus | Odense University Hospital | P2/3 | B |
| Lymfactin® | Herantis Pharma Plc. | P2 | B |
| Pentoxifylline | M.D. Anderson Cancer Center | P2 | B |
| Sodium Selenite | University Health Network, Toronto | P2 | B |
| Tocopherol | M.D. Anderson Cancer Center | P2 | CCC |
| Deupirfenidone | PureTech | P2 | CCC |
| Oxygen | Danish Cancer Society | P2 | CCC |
+9 more in the Lymphedema cohort
Other indications for Indocyanine Green
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Endometrial Carcinoma | — | P4 | BB · 70 |
| Vulva Cancer | — | P4 | BB · 70 |
| Rectal Cancer | — | P3 | BB · 68 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Indocyanine Green in Lymphedema. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/indocyanine-green-lymphedema
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