Floatz Rating
CCC48/100
Confidence
Indicative
Sponsor
Second Affiliated Hospital, School of Medicine, Zhejiang University
Modality
UNKNOWN
Development Phase
Phase 1/2
Status
Dormant
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
33Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT04388033CT.gov Clinical Study of an Dendritic and Glioma Cells Fusion Vaccine With IL-12 for Treatment-naïve GBM Patients. | — | Unknown | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95Moderate confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Immune System Disorder
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Interleukin-12 (this asset) | Second Affiliated Hospital, School of Medicine, Zhejiang University | P1/2 | CCC · 48 |
| Cyclophosphamide | Indapta Therapeutics, INC. | P2 | BB |
| Fludarabine | Indapta Therapeutics, INC. | P2 | BB |
| Lidocaine | Ciusss de L'Est de l'Île de Montréal | P4 | BB |
| Strimvelis | Fondazione Telethon | P4 | B |
| Alemtuzumab | Washington University School of Medicine | P2 | B |
| Thiotepa | Washington University School of Medicine | P2 | B |
| Melphalan | Washington University School of Medicine | P2 | B |
| Ibrutinib | Oncternal Therapeutics, Inc | P3 | B |
+30 more in the Immune System Disorder cohort
Other indications for Interleukin-12
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Primitive Neuroectodermal Tumor | — | P1/2 | CCC · 48 |
| Neuroepithelial Neoplasm | — | P1/2 | CCC · 48 |
| Nervous System Neoplasm | — | P1/2 | CC · 47 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Interleukin-12 in Immune System Disorder. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/interleukin-12-immune-system-disorder
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