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Ioflupane

Parkinsonian Disorder

Floatz Rating
BB64/100
Confidence
Indicative
v0.2
Sponsor
GE Healthcare
Modality
Small molecule
Development Phase
Phase 3
Status
Dormant
Evidence ledger · v0.2

Clinical Evidence

Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
49Moderate confidence
Detailed axis rationale is planned and will be published soon.
TrialPhaseStatusNPrimary endpointReadout
A Study to Evaluate the Diagnostic Efficacy of DaTSCAN™ Ioflupane (123I) Injection in Single Photon Emission Computed Tomography (SPECT) for the Diagnosis of Parkinsonian Syndrome (PS) in Chinese Patients
Completed

Competitive Position

Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.

Same indication · Parkinsonian Disorder

AssetSponsorPhaseRating
Ioflupane (this asset)GE HealthcareP3BB · 64
.Beta.-CitInstitute for Neurodegenerative DisordersP2BBB
8-AZABICYCLO(3.2.1)OCTANE-2-CARBOXYLIC ACID, 3-(4-FLUOROPHENYL)-8-((2E)-3-IODO-2-PROPEN-1-YL)-, METHYL ESTER, (1R,2S,3S,5S)-Alseres Pharmaceuticals, IncP3B
LevodopaInstitute for Neurodegenerative DisordersP2B
PramipexoleInstitute for Neurodegenerative DisordersP2B
LactuloseInstitute of Liver and Biliary Sciences, IndiaN/AD
CarbidopaInstitute for Neurodegenerative DisordersN/AD
RifaximinInstitute of Liver and Biliary Sciences, IndiaN/AD
2-Bromo-?-ergocryptineInstitute of Liver and Biliary Sciences, IndiaN/AD

+2 more in the Parkinsonian Disorder cohort

Other indications for Ioflupane

IndicationSponsorPhaseRating
REM Sleep Behavior DisorderP4BBB · 72
Progressive Supranuclear PalsyP3BB · 69
DementiaP4BB · 69

Scientific Foundation

Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR

Planned for methodology v0.2.

Development Feasibility

How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR

Planned for methodology v0.2.

Commercial Opportunity

Commercial prize: addressable population, unmet need, and the value case for the indication.
NR

Planned for methodology v0.2.

IP & Exclusivity

Exclusivity position, covering patent protection and freedom-to-operate runway.
NR

Planned for methodology v0.2.

Manufacturing & Supply

Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR

Planned for methodology v0.2.

Related assets

Citation

Floatz Terminal. Ioflupane in Parkinsonian Disorder. Methodology v0.2.
Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026.
Accessed July 14, 2026.
https://terminal.floatz.ai/assets/ioflupane-parkinsonian-disorder

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