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Floatz Rating
CCC54/100
Confidence
Indicative
v0.2
Sponsor
Regeneron Pharmaceuticals
Modality
monoclonal_antibody
Development Phase
Phase 2
Status
Active
Evidence ledger · v0.2

Clinical Evidence

Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
48High confidence
Detailed axis rationale is planned and will be published soon.
TrialPhaseStatusNPrimary endpointReadout
Investigation of Ubamatamab Combination Therapy in Adult Participants With Platinum-Resistant Ovarian Cancer
Recruiting
T-cell Therapy in Combination With Nivolumab, Relatlimab and Ipilimumab for Patients With Metastatic Ovarian Cancer
Terminated
A Study to Find Out How Safe REGN5668 is and How Well it Works In Adult Women When Given With Either Cemiplimab, or Cemiplimab + Fianlimab, or Ubamatamab
Recruiting
Nivolumab With or Without Ipilimumab in Treating Patients With Recurrent or High Grade Gynecologic Cancer With Metastatic Peritoneal Carcinomatosis
Completed
Study of REGN4018 (Ubamatamab) Administered Alone or in Combination With Cemiplimab in Adult Patients With Recurrent Ovarian Cancer or Other Recurrent Mucin-16 Expressing (MUC16+) Cancers
Recruiting
BrUOG 354 Nivolumab +/- Ipilimumab for Ovarian and Extra-renal Clear Cell Carcinomas
Active Not Recruiting

Competitive Position

Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
65High confidence
Detailed axis rationale is planned and will be published soon.

Same indication · Fallopian Tube Cancer

AssetSponsorPhaseRating
Ipilimumab (this asset)Regeneron PharmaceuticalsP2CCC · 54
Mirvetuximab SoravtansineAbbVieP3BB
AdriamycinSichuan Baili Pharmaceutical Co., Ltd.P3BB
CarboplatinCancer Institute and Hospital, Chinese Academy of Medical SciencesP3BB
IrinotecanTianjin Medical University Cancer Institute and HospitalP3BB
NogitecanSichuan Baili Pharmaceutical Co., Ltd.P3BB
Cis-Diamminedichloroplatinum IiGOG FoundationP3BB
EpirubicinOncoC4, Inc.P3BB
GlutathioneAlliance for Clinical Trials in OncologyP3BB

+42 more in the Fallopian Tube Cancer cohort

Other indications for Ipilimumab

IndicationSponsorPhaseRating
Metastatic NeoplasmP3BB · 71
MelanomaP4BB · 69
Cutaneous MelanomaP3BB · 69

Scientific Foundation

Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR

Planned for methodology v0.2.

Development Feasibility

How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR

Planned for methodology v0.2.

Commercial Opportunity

Commercial prize: addressable population, unmet need, and the value case for the indication.
NR

Planned for methodology v0.2.

IP & Exclusivity

Exclusivity position, covering patent protection and freedom-to-operate runway.
NR

Planned for methodology v0.2.

Manufacturing & Supply

Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR

Planned for methodology v0.2.

Related assets

Citation

Floatz Terminal. Ipilimumab in Fallopian Tube Cancer. Methodology v0.2.
Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026.
Accessed July 14, 2026.
https://terminal.floatz.ai/assets/ipilimumab-fallopian-tube-cancer

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