Kisspeptin 112-121
Kallmann Syndrome
Floatz Rating
CC47/100
Confidence
Indicative
Sponsor
Massachusetts General Hospital
Modality
UNKNOWN
Development Phase
Phase 1
Status
Dormant
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
32Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT00914823CT.gov Kisspeptin Administration in the Adult | — | Completed | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95Indicative
Detailed axis rationale is planned and will be published soon.
Same indication · Kallmann Syndrome
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Kisspeptin 112-121 (this asset) | Massachusetts General Hospital | P1 | CC · 47 |
| Gnrh | Massachusetts General Hospital | P1 | CC |
Other indications for Kisspeptin 112-121
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Polycystic Ovary Syndrome | — | P1 | CCC · 50 |
| Hypogonadotropic Hypogonadism | — | P1 | CC · 47 |
| Hyperprolactinemia | — | P1 | CC · 47 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Kisspeptin 112-121 in Kallmann Syndrome. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/kisspeptin-112-121-kallmann-syndrome
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