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Floatz Rating
D30/100
Confidence
Indicative
v0.2
Sponsor
Kyverna Therapeutics
Modality
Cell therapy
Development Phase
Unknown
Status
Active
Evidence ledger · v0.2

Clinical Evidence

Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
15Moderate confidence
Detailed axis rationale is planned and will be published soon.
TrialPhaseStatusNPrimary endpointReadout
A Long-Term Follow-Up Study for Participants Previously Treated With KYV-101
Recruiting

Competitive Position

Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.

Same indication · Stiff-Person Syndrome

AssetSponsorPhaseRating
Kyv-101 (this asset)Kyverna TherapeuticsUnkD · 30
CytarabineFred Hutchinson Cancer CenterP2CCC
PrednisoneFred Hutchinson Cancer CenterP2CCC
CamustineFred Hutchinson Cancer CenterP2CCC
MelphalanFred Hutchinson Cancer CenterP2CCC
Anti-Human T-Lymphocyte Immunoglobulin, RabbitFred Hutchinson Cancer CenterP2CCC
EtoposideFred Hutchinson Cancer CenterP2CCC

Other indications for Kyv-101

IndicationSponsorPhaseRating
Primary Progressive Multiple SclerosisP2B · 60
Secondary Progressive Multiple SclerosisP2B · 60
Multiple SclerosisP2CCC · 52

Scientific Foundation

Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR

Planned for methodology v0.2.

Development Feasibility

How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR

Planned for methodology v0.2.

Commercial Opportunity

Commercial prize: addressable population, unmet need, and the value case for the indication.
NR

Planned for methodology v0.2.

IP & Exclusivity

Exclusivity position, covering patent protection and freedom-to-operate runway.
NR

Planned for methodology v0.2.

Manufacturing & Supply

Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR

Planned for methodology v0.2.

Related assets

Citation

Floatz Terminal. Kyv-101 in Stiff-Person Syndrome. Methodology v0.2.
Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026.
Accessed July 14, 2026.
https://terminal.floatz.ai/assets/kyv-101-stiff-person-syndrome

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