Floatz Rating
B57/100
Confidence
Indicative
Sponsor
Mclean Hospital
Modality
Small molecule
Development Phase
Phase 2
Status
Dormant
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
42Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT00719706CT.gov The Use of a Mitochondrial Enhancement Treatment in Bipolar Disorder | — | Completed | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
81High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Bipolar Depression
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| L-Acetyl Carnitine (this asset) | Mclean Hospital | P2 | B · 57 |
| Lurasidone | NeuroRx, Inc. | P4 | A |
| Lithium, Elemental | Dr. Inge Winter | P4 | BBB |
| (±)-2-(O-Chlorophenyl)-2-(Methylamino)Cyclohexanone | Joshua Rosenblat | P4 | BBB |
| Lamotrigine | Stony Brook University | P4 | BBB |
| Quetiapine | Dr. Inge Winter | P4 | BBB |
| Escitalopram | Dr. Inge Winter | P4 | BBB |
| Nrx-101 | NeuroRx, Inc. | P3 | BBB |
| Sertraline | Dr. Inge Winter | P4 | BB |
+42 more in the Bipolar Depression cohort
Other indications for L-Acetyl Carnitine
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Migraine Disorder | — | P4 | B · 62 |
| Alzheimer Disease | — | P4 | B · 58 |
| Sickle Cell Disease | — | P2 | B · 57 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. L-Acetyl Carnitine in Bipolar Depression. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/l-acetyl-carnitine-bipolar-depression
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