Floatz Rating
B57/100
Confidence
Indicative
Sponsor
University Hospital, Basel, Switzerland
Modality
UNKNOWN
Development Phase
Phase 2
Status
Dormant
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
42Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT02018731CT.gov L-citrulline and Metformin in Becker's Muscular Dystrophy | — | Completed | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95Indicative
Detailed axis rationale is planned and will be published soon.
Same indication · Becker Muscular Dystrophy
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| L-Citrulline (this asset) | University Hospital, Basel, Switzerland | P2 | B · 57 |
| (-)-Epicatechin | Craig McDonald, MD | P2 | BB |
| Carvedilol | Catholic University, Italy | P4 | BB |
| Tadalafil | Cedars-Sinai Medical Center | P4 | BB |
| Ataluren | PTC Therapeutics | P3 | BB |
| Lisinopril | Cooperative International Neuromuscular Research Group | P2/3 | B |
| Corpril | Catholic University, Italy | P4 | B |
| Sevasemten | Edgewise Therapeutics, Inc. | P2 | B |
| coq10 | Cooperative International Neuromuscular Research Group | P2/3 | B |
+10 more in the Becker Muscular Dystrophy cohort
Other indications for L-Citrulline
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Sickle Cell Disease | — | P3 | B · 60 |
| Essential Hypertension | — | P1 | CC · 47 |
| MELAS Syndrome | — | P1 | CC · 47 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. L-Citrulline in Becker Muscular Dystrophy. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/l-citrulline-becker-muscular-dystrophy
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