Floatz Rating
CCC53/100
Confidence
Indicative
Sponsor
Duke University
Modality
Small molecule
Development Phase
Phase 2
Status
Dormant
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
38Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT03436433CT.gov Seizure Prophylaxis in Patients With Glioma or Brain Metastasis | — | Terminated | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Brain Glioma
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Lacosamide (this asset) | Duke University | P2 | CCC · 53 |
| FDOPA | University of Alberta | P3 | B |
| Ribociclib | St. Joseph's Hospital and Medical Center, Phoenix | P1 | B |
| Ganciclovir | Huazhong University of Science and Technology | P2 | B |
| Everolimus | St. Joseph's Hospital and Medical Center, Phoenix | P1 | B |
| Aglatimagene Besadenovec | Huazhong University of Science and Technology | P2 | B |
| gp96 | Cure&Sure Biotech Co., LTD | P2 | CCC |
| g207 | Pediatric Brain Tumor Consortium | P2 | CCC |
| V-Boost | Immunitor LLC | P2 | CCC |
+14 more in the Brain Glioma cohort
Other indications for Lacosamide
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Focal Epilepsy | — | P4 | A · 80 |
| Epilepsy | — | P4 | BBB · 74 |
| Migraine Disorder | — | P3 | BB · 67 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Lacosamide in Brain Glioma. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/lacosamide-brain-glioma
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