Floatz Rating
CC45/100
Confidence
Indicative
Sponsor
Dompé Farmaceutici S.p.A
Modality
UNKNOWN
Development Phase
Phase 2
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
30Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT05368402CT.gov Clinical Trial on Ladarixin Adjunctive Therapy to Improve Glycemic Control in Type 1 Diabetes. | — | Terminated | — | — | — |
NCT05035368CT.gov Ladarixin as Adjunctive Therapy to Improve Insulin Sensitivity and Glucometabolic Outcomes in Type 1 Diabetes | — | Withdrawn | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95Moderate confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Type 1 Diabetes Mellitus
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Ladarixin (this asset) | Dompé Farmaceutici S.p.A | P2 | CC · 45 |
| Metformin | Heba M. Ismail | P4 | A |
| Liraglutide | Dasman Diabetes Institute | P4 | BBB |
| Tirzepatide | Royal North Shore Hospital | P4 | BBB |
| Semaglutide | Nordsjaellands Hospital | P3 | BB |
| ct-868 | Carmot Therapeutics, Inc. | P2 | BB |
| Glucagon | Charite University, Berlin, Germany | P3 | B |
| .Alpha.-1 Protease Inhibitor | Grifols Therapeutics LLC | P2 | B |
| Physiologic Sodium Chloride Solution | Charite University, Berlin, Germany | P3 | B |
+13 more in the Type 1 Diabetes Mellitus cohort
Other indications for Ladarixin
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Non-Small Cell Lung Carcinoma | — | P2 | NR |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Ladarixin in Type 1 Diabetes Mellitus. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/ladarixin-type-1-diabetes-mellitus
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