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Floatz Rating
CC43/100
Confidence
Indicative
v0.2
Sponsor
M.D. Anderson Cancer Center
Modality
Small molecule
Development Phase
Phase 1
Status
Active
Evidence ledger · v0.2

Clinical Evidence

Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
28Indicative
Detailed axis rationale is planned and will be published soon.
TrialPhaseStatusNPrimary endpointReadout
A Pilot Study to Assess Changes in Tumor Biology Following Second-line Treatment With Pembrolizumab Plus Lenvatinib in Patients With Advanced Pancreatic Ductal Adenocarcinoma
Active Not Recruiting

Competitive Position

Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
89High confidence
Detailed axis rationale is planned and will be published soon.

Same indication · Adenocarcinoma

AssetSponsorPhaseRating
Lenvatinib (this asset)M.D. Anderson Cancer CenterP1CC · 43
Cis-Diamminedichloroplatinum IiMayo ClinicP4BBB
CarboplatinBlueprint Medicines CorporationP4BBB
IrinotecanUniversity of ChicagoP2BBB
CyclophosphamideM.D. Anderson Cancer CenterP3BB
IcotinibBetta Pharmaceuticals Co., Ltd.P4BB
DesfluraneUniversity of ZurichP4BB
FluorouracilumUniversity of ChicagoP2BB
CrizotinibUniversity of BirminghamP2BB

+42 more in the Adenocarcinoma cohort

Other indications for Lenvatinib

IndicationSponsorPhaseRating
Portal Vein ThrombosisP4BBB · 73
Ovarian CarcinomaP4BB · 70
Hepatocellular CarcinomaP4BB · 69

Scientific Foundation

Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR

Planned for methodology v0.2.

Development Feasibility

How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR

Planned for methodology v0.2.

Commercial Opportunity

Commercial prize: addressable population, unmet need, and the value case for the indication.
NR

Planned for methodology v0.2.

IP & Exclusivity

Exclusivity position, covering patent protection and freedom-to-operate runway.
NR

Planned for methodology v0.2.

Manufacturing & Supply

Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR

Planned for methodology v0.2.

Related assets

Citation

Floatz Terminal. Lenvatinib in Adenocarcinoma. Methodology v0.2.
Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026.
Accessed July 14, 2026.
https://terminal.floatz.ai/assets/lenvatinib-adenocarcinoma

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