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Floatz Rating
B59/100
Confidence
Indicative
v0.2
Sponsor
University Medical Center Groningen
Modality
Small molecule
Development Phase
Phase 4 / Approved
Status
Active
Evidence ledger · v0.2

Clinical Evidence

Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
55Moderate confidence
Detailed axis rationale is planned and will be published soon.
TrialPhaseStatusNPrimary endpointReadout
OPTI - DOSE: Optimal Dosing of Oral Anticancer Drugs in Older Adults
Unknown
Study of Favezelimab Coformulated With Pembrolizumab (MK-4280A) in Participants With Selected Solid Tumors (MK-4280A-010)
Completed
Lenvatinib, Pembrolizumab, and Paclitaxel for Treatment of Recurrent Endometrial, Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Active Not Recruiting

Competitive Position

Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
65High confidence
Detailed axis rationale is planned and will be published soon.

Same indication · Endometrial Carcinoma

AssetSponsorPhaseRating
Lenvatinib (this asset)University Medical Center GroningenApprovedB · 59
Indocyanine GreenIstanbul UniversityP4BB
AdriamycinAstraZenecaP3BB
OlaparibQilu Pharmaceutical Co., Ltd.P4BB
PalbociclibUniversity Medical Center GroningenP4BB
NivestimMayo ClinicP3B
RilvegostomigAstraZenecaP3B
CapivasertibM.D. Anderson Cancer CenterP2B
CyclophosphamideSutro Biopharma, Inc.P3B

+42 more in the Endometrial Carcinoma cohort

Other indications for Lenvatinib

IndicationSponsorPhaseRating
Portal Vein ThrombosisP4BBB · 73
Ovarian CarcinomaP4BB · 70
Hepatocellular CarcinomaP4BB · 69

Scientific Foundation

Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR

Planned for methodology v0.2.

Development Feasibility

How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR

Planned for methodology v0.2.

Commercial Opportunity

Commercial prize: addressable population, unmet need, and the value case for the indication.
NR

Planned for methodology v0.2.

IP & Exclusivity

Exclusivity position, covering patent protection and freedom-to-operate runway.
NR

Planned for methodology v0.2.

Manufacturing & Supply

Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR

Planned for methodology v0.2.

Related assets

Citation

Floatz Terminal. Lenvatinib in Endometrial Carcinoma. Methodology v0.2.
Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026.
Accessed July 14, 2026.
https://terminal.floatz.ai/assets/lenvatinib-endometrial-carcinoma

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