Letrozole
Invasive Ductal Breast Carcinoma
Floatz Rating
BBB72/100
Confidence
Indicative
Sponsor
University of Washington
Modality
Small molecule
Development Phase
Phase 4 / Approved
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
57Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT02221999CT.gov Weekly Paclitaxel and Cisplatin to Treat Hormone Receptor Positive and Triple Negative Breast Cancer Patients | — | Active Not Recruiting | — | — | — |
NCT01791478CT.gov BYL719 and Letrozole in Post-Menopausal Patients With Hormone Receptor-Positive Metastatic Breast Cancer | — | Active Not Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Invasive Ductal Breast Carcinoma
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Letrozole (this asset) | University of Washington | Approved | BBB · 72 |
| Carboplatin | GBG Forschungs GmbH | P3 | BBB |
| Cyclophosphamide | UMC Utrecht | P3 | BB |
| Cis-Diamminedichloroplatinum Ii | RenJi Hospital | P3 | BB |
| Pertuzumab | GBG Forschungs GmbH | P3 | BB |
| Trastuzumab | GBG Forschungs GmbH | P3 | BB |
| Epirubicin | GBG Forschungs GmbH | P3 | BB |
| Fulvestrant | G1 Therapeutics, Inc. | P3 | BB |
| Adriamycin | GBG Forschungs GmbH | P3 | BB |
+27 more in the Invasive Ductal Breast Carcinoma cohort
Other indications for Letrozole
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Infertility Disorder | — | P4 | BBB · 79 |
| Anovulation | — | P4 | BBB · 78 |
| Invasive Breast Carcinoma | — | P4 | BBB · 74 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Citation
Floatz Terminal. Letrozole in Invasive Ductal Breast Carcinoma. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 13, 2026. https://terminal.floatz.ai/assets/letrozole-invasive-ductal-breast-carcinoma
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