Floatz Rating
C39/100
Confidence
Indicative
Sponsor
University of Rochester
Modality
Small molecule
Development Phase
Early Phase 1
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
24Indicative
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT05530655CT.gov A Study to Determine the Preferred Dose of the Drug, Lisinopril, for Preventing Urinary Toxicity Following Radiotherapy for Prostate Cancer | — | Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Urinary System Disorder
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Lisinopril (this asset) | University of Rochester | Early P1 | C · 39 |
| Rocuronium Ion | Rainer Lenhardt | P4 | BB |
| Goserelin | University College, London | P3 | BB |
| Leuporelin | University College, London | P3 | BB |
| Bicalutamide | University College, London | P3 | B |
| Zoledronate | Alliance for Clinical Trials in Oncology | P3 | B |
| Marcaine | Hans Bahlmann | P3 | B |
| Nepenthe | Hans Bahlmann | P3 | B |
| Lidocaine | Hans Bahlmann | P3 | B |
+9 more in the Urinary System Disorder cohort
Other indications for Lisinopril
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Diabetic Kidney Disease | — | P3 | BB · 64 |
| Hypertensive Disorder | — | P3 | BB · 64 |
| Becker Muscular Dystrophy | — | P2/3 | B · 61 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Lisinopril in Urinary System Disorder. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/lisinopril-urinary-system-disorder
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