Floatz Rating
B60/100
Confidence
Indicative
Sponsor
Negovsky Reanimatology Research Institute
Modality
Small molecule
Development Phase
Phase 3
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
45Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT05126238CT.gov A Lithium-Based Medication to Improve Neurological Outcomes After Surgical Carotid Reconstruction | — | Terminated | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Carotid Stenosis
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Lithium, Elemental (this asset) | Negovsky Reanimatology Research Institute | P3 | B · 60 |
| Clopidogrel | Asan Medical Center | P4 | BB |
| Atorvastatin | Columbia University | P4 | BB |
| Ephedrine, Anhydrous | University Hospital, Clermont-Ferrand | P4 | BB |
| Cilostazol | Asan Medical Center | P4 | BB |
| Aspirin | Asan Medical Center | P4 | BB |
| Gadobutrol | Bayer | P3 | BB |
| BAY86-4875 | Bayer | P3 | BB |
| Amlodipine | Russian Cardiology Research and Production Center | P4 | BB |
+17 more in the Carotid Stenosis cohort
Other indications for Lithium, Elemental
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Bipolar I Disorder | — | P4 | BBB · 77 |
| Bipolar Depression | — | P4 | BBB · 75 |
| Manic Bipolar Affective Disorder | — | P4 | BBB · 75 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Lithium, Elemental in Carotid Stenosis. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/lithium-elemental-carotid-stenosis
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