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Floatz Rating
CC43/100
Confidence
Indicative
v0.2
Sponsor
University Health Network, Toronto
Modality
Small molecule
Development Phase
Phase 1
Status
Active
Evidence ledger · v0.2

Clinical Evidence

Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
28Indicative
Detailed axis rationale is planned and will be published soon.
TrialPhaseStatusNPrimary endpointReadout
Phase 1 Study of RP-6306 With Carboplatin and Paclitaxel in TP53 Ovarian and Uterine Cancer
Active Not Recruiting

Competitive Position

Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.

Same indication · Uterine Cancer

AssetSponsorPhaseRating
Lunresertib (this asset)University Health Network, TorontoP1CC · 43
GALFERSunnybrook Health Sciences CentreP4BB
Phosphonic Acid, P-[3-[[(2R,3R)-2-[(1R)-1-[3,5-Bis(Trifluoromethyl)Phenyl]Ethoxy]-3-(4-Fluorophenyl)-4-Morpholinyl]Methyl]-2,5-Dihydro-5-Oxo-1H-1,2,4-Triazol-1-Yl]-Gynecologic Oncology AssociatesP4BB
NivolumabNational Cancer Institute (NCI)P2B
MarcaineUniversity of California, IrvineP3B
SirexatamabLeap Therapeutics, Inc.P2B
AtezolizumabGradalis, Inc.P2B
DurvalumabMary Crowley Medical Research CenterP2B
CabozantinibNational Cancer Institute (NCI)P2B

+42 more in the Uterine Cancer cohort

Other indications for Lunresertib

IndicationSponsorPhaseRating
Breast CancerP2CC · 46
Ovarian CancerP1CC · 41
Metastatic Malignant NeoplasmP1C · 39

Scientific Foundation

Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR

Planned for methodology v0.2.

Development Feasibility

How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR

Planned for methodology v0.2.

Commercial Opportunity

Commercial prize: addressable population, unmet need, and the value case for the indication.
NR

Planned for methodology v0.2.

IP & Exclusivity

Exclusivity position, covering patent protection and freedom-to-operate runway.
NR

Planned for methodology v0.2.

Manufacturing & Supply

Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR

Planned for methodology v0.2.

Related assets

Citation

Floatz Terminal. Lunresertib in Uterine Cancer. Methodology v0.2.
Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026.
Accessed July 14, 2026.
https://terminal.floatz.ai/assets/lunresertib-uterine-cancer

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