Floatz Rating
B61/100
Confidence
Indicative
Sponsor
National Taiwan University Hospital
Modality
Small molecule
Development Phase
Phase 2/3
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
46Moderate confidence
Detailed axis rationale is planned and will be published soon.
No trial-level evidence is linked to this axis yet.
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Childhood-Onset Epilepsy Syndrome
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Melatonin (this asset) | National Taiwan University Hospital | P2/3 | B · 61 |
| Retigabine | Xenon Pharmaceuticals Inc. | P3 | CCC |
| Sulthiame | University Hospital, Angers | Unk | D |
| Mgcnd00Ep1 | MGC Pharmaceuticals d.o.o | P2 | NR |
| Perampanel | Eisai Inc. | P2 | NR |
Other indications for Melatonin
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Traumatic Brain Injury | — | P4 | BBB · 74 |
| Bipolar Disorder | — | P4 | BBB · 72 |
| Circadian Rhythm Sleep Disorder | — | P4 | BB · 69 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Melatonin in Childhood-Onset Epilepsy Syndrome. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/melatonin-childhood-onset-epilepsy-syndrome
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