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Floatz Rating
B57/100
Confidence
Indicative
v0.2
Sponsor
Dennis Bregner Zetner
Modality
Small molecule
Development Phase
Phase 2
Status
Dormant
Evidence ledger · v0.2

Clinical Evidence

Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
42Moderate confidence
Detailed axis rationale is planned and will be published soon.
TrialPhaseStatusNPrimary endpointReadout
Melatonin Cream Against Acute Radiation Dermatitis in Patients With Early Breast Cancer
Completed

Competitive Position

Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.

Same indication · Radiodermatitis

AssetSponsorPhaseRating
Melatonin (this asset)Dennis Bregner ZetnerP2B · 57
Olea Europaea OilCairo UniversityP4BB
UreaUniversity of BrasiliaP3BB
FlosteronCairo UniversityP4BB
Chamomilla RecutitaUniversity of BrasiliaP3BB
MometasoneNorth Central Cancer Treatment GroupP3BB
CicadermaCentre Leon BerardP3B
Urtica Comp.University of BernP2B
Household BleachStanford UniversityP2B

+24 more in the Radiodermatitis cohort

Other indications for Melatonin

IndicationSponsorPhaseRating
Traumatic Brain InjuryP4BBB · 74
Bipolar DisorderP4BBB · 72
Circadian Rhythm Sleep DisorderP4BB · 69

Scientific Foundation

Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR

Planned for methodology v0.2.

Development Feasibility

How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR

Planned for methodology v0.2.

Commercial Opportunity

Commercial prize: addressable population, unmet need, and the value case for the indication.
NR

Planned for methodology v0.2.

IP & Exclusivity

Exclusivity position, covering patent protection and freedom-to-operate runway.
NR

Planned for methodology v0.2.

Manufacturing & Supply

Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR

Planned for methodology v0.2.

Related assets

Citation

Floatz Terminal. Melatonin in Radiodermatitis. Methodology v0.2.
Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026.
Accessed July 14, 2026.
https://terminal.floatz.ai/assets/melatonin-radiodermatitis

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