Floatz Rating
B60/100
Confidence
Indicative
Sponsor
GRIN Therapeutics, Inc.
Modality
Small molecule
Development Phase
Phase 2
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
45High confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT06975605CT.gov Phase 1, Open-label, Drug-drug Interaction Study to Assess Effect Between Radiprodil and the Co-administered Drugs. | — | Completed | — | — | — |
NCT04912115CT.gov Randomized, Double-Blind, Active Placebo-Controlled Study of Ketamine to Treat Levodopa-Induced Dyskinesia | — | Suspended | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
89High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Nervous System Disorder
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Midazolam (this asset) | GRIN Therapeutics, Inc. | P2 | B · 60 |
| Ginkgolide | Second Affiliated Hospital, School of Medicine, Zhejiang University | P4 | BB |
| Guanfacine | Maimonides Medical Center | P4 | BB |
| Brexpiprazole | Otsuka Pharmaceutical Development & Commercialization, Inc. | P3 | BB |
| Live Combined Bifidobacterium,Lactobacillus And Enterococcus Capsules | Beijing Friendship Hospital | P4 | BB |
| 3-N-BUTYLPHTHALIDE | Qianfoshan Hospital | P4 | BB |
| Live Combined Bifidobacterium | Beijing Friendship Hospital | P4 | BB |
| D-Thioctic Acid | Ain Shams University | P4 | BB |
| Aspirin | Ipsen | P3 | BB |
+42 more in the Nervous System Disorder cohort
Other indications for Midazolam
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Neuralgia | — | P4 | BBB · 75 |
| Gastrointestinal Stromal Tumor | — | P4 | BBB · 75 |
| Choledocholithiasis | — | P4 | BBB · 73 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
- GinkgolideSecond Affiliated Hospital, School of Medicine, Zhejiang UniversityBB
- GuanfacineMaimonides Medical CenterBB
- BrexpiprazoleOtsuka Pharmaceutical Development & Commercialization, Inc.BB
- Live Combined Bifidobacterium,Lactobacillus And Enterococcus CapsulesBeijing Friendship HospitalBB
- 3-N-BUTYLPHTHALIDEQianfoshan HospitalBB
Citation
Floatz Terminal. Midazolam in Nervous System Disorder. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/midazolam-nervous-system-disorder
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