Floatz Rating
BB64/100
Confidence
Indicative
Sponsor
Corcept Therapeutics
Modality
Small molecule
Development Phase
Phase 3
Status
Dormant
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
55High confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT00637494CT.gov A Study of Mifepristone vs. Placebo in the Treatment of Patients With Major Depression With Psychotic Features | — | Terminated | — | — | — |
NCT00128505CT.gov An International Extension Study of Corlux for Recurrent Psychotic Symptoms in Psychotic Major Depression | — | Completed | — | — | — |
NCT00128479CT.gov A United States Study of the Safety and Tolerability of Corlux for Psychotic Symptoms in Psychotic Major Depression | — | Completed | — | — | — |
NCT00130676CT.gov A United States Study of Corlux for Psychotic Symptoms in Psychotic Major Depression | — | Completed | — | — | — |
NCT00725270CT.gov Treatment of Schizoaffective Disorder Using Mifepristone | — | Terminated | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
81High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Psychotic Disorder
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Mifepristone (this asset) | Corcept Therapeutics | P3 | BB · 64 |
| Risperidone | Northwell Health | P4 | BBB |
| Olanzapine | Shanghai Jiao Tong University School of Medicine | P4 | BBB |
| Paliperidone | Consorcio Centro de Investigación Biomédica en Red (CIBER) | P4 | BBB |
| Eukystol | Fundación Pública Andaluza para la gestión de la Investigación en Sevilla | P4 | BBB |
| Asenapine | Centre de Recherche de l'Institut Universitaire en Santé Mentale de Québec | P4 | BBB |
| Simvastatin | Mclean Hospital | P4 | BBB |
| Sertraline | Northwell Health | P4 | BBB |
| Quetiapine | Shanghai Jiao Tong University School of Medicine | P4 | BBB |
+42 more in the Psychotic Disorder cohort
Other indications for Mifepristone
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Major Depressive Disorder | — | P3 | B · 63 |
| Cushing Syndrome | — | P4 | B · 62 |
| Type 2 Diabetes Mellitus | — | P4 | B · 61 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
- RisperidoneNorthwell HealthBBB
- OlanzapineShanghai Jiao Tong University School of MedicineBBB
- PaliperidoneConsorcio Centro de Investigación Biomédica en Red (CIBER)BBB
- EukystolFundación Pública Andaluza para la gestión de la Investigación en SevillaBBB
- AsenapineCentre de Recherche de l'Institut Universitaire en Santé Mentale de QuébecBBB
Citation
Floatz Terminal. Mifepristone in Psychotic Disorder. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 13, 2026. https://terminal.floatz.ai/assets/mifepristone-psychotic-disorder
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