Minocycline
Methicillin-Resistant Staphylococcus Aureus Infectious Disease
Explore 3 assets in Methicillin-Resistant Staphylococcus Aureus Infectious Disease →Floatz Rating
CCC53/100
Confidence
Indicative
Sponsor
University of North Carolina, Chapel Hill
Modality
Small molecule
Development Phase
Phase 2
Status
Dormant
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
38Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT01349192CT.gov Early Methicillin-resistant Staphylococcus Aureus (MRSA) Therapy in Cystic Fibrosis (CF) | — | Terminated | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95Indicative
Detailed axis rationale is planned and will be published soon.
Same indication · Methicillin-Resistant Staphylococcus Aureus Infectious Disease
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Minocycline (this asset) | University of North Carolina, Chapel Hill | P2 | CCC · 53 |
| Trimethoprim | University of North Carolina, Chapel Hill | P4 | BBB |
| Sulfamethoxazole | University of North Carolina, Chapel Hill | P4 | BBB |
| Rifaldazine | Johns Hopkins University | P4 | BB |
| Vancomycin | Savara Inc. | P3 | BB |
| Cefadroxil Anhydrous | Mayo Clinic | P4 | BB |
| Cephalexin | Mayo Clinic | P4 | BB |
| Doxycycline | Mayo Clinic | P4 | B |
| Chlorhexidine | University of North Carolina, Chapel Hill | P2 | CCC |
+1 more in the Methicillin-Resistant Staphylococcus Aureus Infectious Disease cohort
Other indications for Minocycline
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Mood Disorder | — | P4 | BBB · 73 |
| Bipolar Depression | — | P4 | BB · 70 |
| Schizophrenia | — | P4 | BB · 68 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Minocycline in Methicillin-Resistant Staphylococcus Aureus Infectious Disease. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/minocycline-methicillin-resistant-staphylococcus-aureus-infectious-disease
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