Mitoquinol Mesilate
Cognitive Disorder
Floatz Rating
CCC55/100
Confidence
Indicative
Sponsor
Mclean Hospital
Modality
Small molecule
Development Phase
Phase 2/3
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
42Indicative
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT06191965CT.gov MitoQ for Early-phase Schizophrenia-spectrum Disorder and Mitochondrial Dysfunction | — | Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
81High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Cognitive Disorder
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Mitoquinol Mesilate (this asset) | Mclean Hospital | P2/3 | CCC · 55 |
| Nicotine | University of Southern California | P2 | BBB |
| Oxybutynin | University of Alberta | P4 | BBB |
| Rivastigmine | VA Office of Research and Development | P4 | BB |
| Metformin | Fudan University | P4 | BB |
| Quetiapine | Emory University | P4 | BB |
| Levodopa | Vanderbilt University Medical Center | P4 | BB |
| Benzeneethanamine, N-Ethyl-?-Methyl-4-(Trifluoromethyl)-, Hydrochloride, (±)- | University of Oxford | P4 | BB |
| Egb 761® | Ipsen | P4 | BB |
+42 more in the Cognitive Disorder cohort
Other indications for Mitoquinol Mesilate
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Schizophrenia | — | P2/3 | B · 57 |
| Mitochondrial Disease | — | P2/3 | B · 57 |
| Amyotrophic Lateral Sclerosis | — | P2 | B · 57 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Citation
Floatz Terminal. Mitoquinol Mesilate in Cognitive Disorder. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 13, 2026. https://terminal.floatz.ai/assets/mitoquinol-mesilate-cognitive-disorder
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